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Enhanced and prolonged baculovirus-mediated expression by incorporating recombinase system and in cis elements: a comparative study
Baculovirus (BV) is a promising gene vector but mediates transient expression. To prolong the expression, we developed a binary system whereby the transgene in the substrate BV was excised by the recombinase (ΦC31o, Cre or FLPo) expressed by a second BV and recombined into smaller minicircle. The re...
Autores principales: | Sung, Li-Yu, Chen, Chiu-Ling, Lin, Shih-Yeh, Hwang, Shiaw-Min, Lu, Chia-Hsin, Li, Kuei-Chang, Lan, Alice S., Hu, Yu-Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737544/ https://www.ncbi.nlm.nih.gov/pubmed/23716635 http://dx.doi.org/10.1093/nar/gkt442 |
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