Modelling of crowded polymers elucidate effects of double-strand breaks in topological domains of bacterial chromosomes

Using numerical simulations of pairs of long polymeric chains confined in microscopic cylinders, we investigate consequences of double-strand DNA breaks occurring in independent topological domains, such as these constituting bacterial chromosomes. Our simulations show a transition between segregate...

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Detalles Bibliográficos
Autores principales: Dorier, Julien, Stasiak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737558/
https://www.ncbi.nlm.nih.gov/pubmed/23742906
http://dx.doi.org/10.1093/nar/gkt480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737558/
https://www.ncbi.nlm.nih.gov/pubmed/23742906
http://dx.doi.org/10.1093/nar/gkt480

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