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Modelling of crowded polymers elucidate effects of double-strand breaks in topological domains of bacterial chromosomes
Using numerical simulations of pairs of long polymeric chains confined in microscopic cylinders, we investigate consequences of double-strand DNA breaks occurring in independent topological domains, such as these constituting bacterial chromosomes. Our simulations show a transition between segregate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737558/ https://www.ncbi.nlm.nih.gov/pubmed/23742906 http://dx.doi.org/10.1093/nar/gkt480 |