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ATHLATES: accurate typing of human leukocyte antigen through exome sequencing

Human leukocyte antigen (HLA) typing at the allelic level can in theory be achieved using whole exome sequencing (exome-seq) data with no added cost but has been hindered by its computational challenge. We developed ATHLATES, a program that applies assembly, allele identification and allelic pair in...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Yang, Xiao, Duffy, Brian, Mohanakumar, Thalachallour, Mitra, Robi D., Zody, Michael C., Pfeifer, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737559/
https://www.ncbi.nlm.nih.gov/pubmed/23748956
http://dx.doi.org/10.1093/nar/gkt481