Discovering high-resolution patterns of differential DNA methylation that correlate with gene expression changes

Methylation of the CpG-rich region (CpG island) overlapping a gene’s promoter is a generally accepted mechanism for silencing expression. While recent technological advances have enabled measurement of DNA methylation and expression changes genome-wide, only modest correlations between differential...

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Detalles Bibliográficos
Autores principales: VanderKraats, Nathan D., Hiken, Jeffrey F., Decker, Keith F., Edwards, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737560/
https://www.ncbi.nlm.nih.gov/pubmed/23748561
http://dx.doi.org/10.1093/nar/gkt482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737560/
https://www.ncbi.nlm.nih.gov/pubmed/23748561
http://dx.doi.org/10.1093/nar/gkt482

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