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Discovering high-resolution patterns of differential DNA methylation that correlate with gene expression changes
Methylation of the CpG-rich region (CpG island) overlapping a gene’s promoter is a generally accepted mechanism for silencing expression. While recent technological advances have enabled measurement of DNA methylation and expression changes genome-wide, only modest correlations between differential...
Autores principales: | VanderKraats, Nathan D., Hiken, Jeffrey F., Decker, Keith F., Edwards, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737560/ https://www.ncbi.nlm.nih.gov/pubmed/23748561 http://dx.doi.org/10.1093/nar/gkt482 |
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