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Investigation of DNA sequence recognition by a streptomycete MarR family transcriptional regulator through surface plasmon resonance and X-ray crystallography

Consistent with their complex lifestyles and rich secondary metabolite profiles, the genomes of streptomycetes encode a plethora of transcription factors, the vast majority of which are uncharacterized. Herein, we use Surface Plasmon Resonance (SPR) to identify and delineate putative operator sites...

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Detalles Bibliográficos
Autores principales: Stevenson, Clare E. M., Assaad, Aoun, Chandra, Govind, Le, Tung B. K., Greive, Sandra J., Bibb, Mervyn J., Lawson, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737563/
https://www.ncbi.nlm.nih.gov/pubmed/23748564
http://dx.doi.org/10.1093/nar/gkt523