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Basophile: Accurate Fragment Charge State Prediction Improves Peptide Identification Rates
In shotgun proteomics, database search algorithms rely on fragmentation models to predict fragment ions that should be observed for a given peptide sequence. The most widely used strategy (Naive model) is oversimplified, cleaving all peptide bonds with equal probability to produce fragments of all c...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737598/ https://www.ncbi.nlm.nih.gov/pubmed/23499924 http://dx.doi.org/10.1016/j.gpb.2012.11.004 |