Basophile: Accurate Fragment Charge State Prediction Improves Peptide Identification Rates

In shotgun proteomics, database search algorithms rely on fragmentation models to predict fragment ions that should be observed for a given peptide sequence. The most widely used strategy (Naive model) is oversimplified, cleaving all peptide bonds with equal probability to produce fragments of all c...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Dasari, Surendra, Chambers, Matthew C., Holman, Jerry D., Chen, Kan, Liebler, Daniel C., Orton, Daniel J., Purvine, Samuel O., Monroe, Matthew E., Chung, Chang Y., Rose, Kristie L., Tabb, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737598/
https://www.ncbi.nlm.nih.gov/pubmed/23499924
http://dx.doi.org/10.1016/j.gpb.2012.11.004

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