Cooperative Unfolding of Compact Conformations of the Intrinsically Disordered Protein Osteopontin

[Image: see text] Intrinsically disordered proteins (IDPs) constitute a class of biologically active proteins that lack defined tertiary and often secondary structure. The IDP Osteopontin (OPN), a cytokine involved in metastasis of several types of cancer, is shown to simultaneously sample extended,...

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Detalles Bibliográficos
Autores principales: Kurzbach, Dennis, Platzer, Gerald, Schwarz, Thomas C., Henen, Morkos A., Konrat, Robert, Hinderberger, Dariush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737600/
https://www.ncbi.nlm.nih.gov/pubmed/23848319
http://dx.doi.org/10.1021/bi400502c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737600/
https://www.ncbi.nlm.nih.gov/pubmed/23848319
http://dx.doi.org/10.1021/bi400502c

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