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Lessons from two prevalent amyloidoses—what amylin and Aβ have in common

The amyloidogenic peptide Aβ plays a key role in Alzheimer's disease (AD) forming insoluble aggregates in the brain. The peptide shares its amyloidogenic properties with amylin that forms aggregates in the pancreas of patients with Type 2 Diabetes mellitus (T2DM). While epidemiological studies...

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Detalles Bibliográficos
Autores principales: Götz, Jürgen, Lim, Yun-An, Eckert, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737661/
https://www.ncbi.nlm.nih.gov/pubmed/23964237
http://dx.doi.org/10.3389/fnagi.2013.00038