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Epigenetic alteration: new insights moving from tissue to plasma – the example of PCDH10 promoter methylation in colorectal cancer

BACKGROUND: Tumour-released DNA in blood represents a promising biomarker for cancer detection. Although epigenetic alterations such as aberrant promoter methylation represent an appealing perspective, the discordance existing between frequencies of alterations found in DNA extracted from tumour tis...

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Detalles Bibliográficos
Autores principales: Danese, E, Minicozzi, A M, Benati, M, Montagnana, M, Paviati, E, Salvagno, G L, Gusella, M, Pasini, F, Guidi, G C, Lippi, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738140/
https://www.ncbi.nlm.nih.gov/pubmed/23839493
http://dx.doi.org/10.1038/bjc.2013.351