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KIT, NRAS and BRAF mutations in sinonasal mucosal melanoma: a study of 56 cases

BACKGROUND: Mucosal melanomas in the head and neck region are most frequently located in the nasal cavity and paranasal sinuses. Sinonasal mucosal melanoma (SNMM) comprises <1% of all melanomas. The aim was to determine the KIT, NRAS and BRAF mutation frequencies in a large series of primary SNMM...

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Detalles Bibliográficos
Autores principales: Zebary, A, Jangard, M, Omholt, K, Ragnarsson-Olding, B, Hansson, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738146/
https://www.ncbi.nlm.nih.gov/pubmed/23860532
http://dx.doi.org/10.1038/bjc.2013.373