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Downregulation of miR-302c and miR-520c by 1,25(OH)2D3 treatment enhances the susceptibility of tumour cells to natural killer cell-mediated cytotoxicity

BACKGROUND: NKG2D recognises several ligands, including polymorphic major histocompatibility complex class I chain-related chain-related proteins A and B (MICA/B) and unique long 16-binding proteins (ULBPs). These ligands are present on cancer cells and are recognised by NKG2D in a cell-structure-se...

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Detalles Bibliográficos
Autores principales: Min, D, Lv, X-b, Wang, X, Zhang, B, Meng, W, Yu, F, Hu, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738147/
https://www.ncbi.nlm.nih.gov/pubmed/23820258
http://dx.doi.org/10.1038/bjc.2013.337