Gene Expression Regulation by Upstream Open Reading Frames and Human Disease

Upstream open reading frames (uORFs) are major gene expression regulatory elements. In many eukaryotic mRNAs, one or more uORFs precede the initiation codon of the main coding region. Indeed, several studies have revealed that almost half of human transcripts present uORFs. Very interesting examples...

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Detalles Bibliográficos
Autores principales: Barbosa, Cristina, Peixeiro, Isabel, Romão, Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738444/
https://www.ncbi.nlm.nih.gov/pubmed/23950723
http://dx.doi.org/10.1371/journal.pgen.1003529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738444/
https://www.ncbi.nlm.nih.gov/pubmed/23950723
http://dx.doi.org/10.1371/journal.pgen.1003529

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