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Binding Polymorphism in the DNA Bound State of the Pdx1 Homeodomain
The subtle effects of DNA-protein recognition are illustrated in the homeodomain fold. This is one of several small DNA binding motifs that, in spite of limited DNA binding specificity, adopts crucial, specific roles when incorporated in a transcription factor. The homeodomain is composed of a 3-hel...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738460/ https://www.ncbi.nlm.nih.gov/pubmed/23950697 http://dx.doi.org/10.1371/journal.pcbi.1003160 |