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Binding Polymorphism in the DNA Bound State of the Pdx1 Homeodomain

The subtle effects of DNA-protein recognition are illustrated in the homeodomain fold. This is one of several small DNA binding motifs that, in spite of limited DNA binding specificity, adopts crucial, specific roles when incorporated in a transcription factor. The homeodomain is composed of a 3-hel...

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Detalles Bibliográficos
Autores principales: Babin, Volodymyr, Wang, Dongli, Rose, Robert B., Sagui, Celeste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738460/
https://www.ncbi.nlm.nih.gov/pubmed/23950697
http://dx.doi.org/10.1371/journal.pcbi.1003160