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Induction of Mouse Melioidosis with Meningitis by CD11b(+) Phagocytic Cells Harboring Intracellular B. pseudomallei as a Trojan Horse

BACKGROUND: Approximately 3–5% of patients with melioidosis manifest CNS symptoms; however, the clinical data regarding neurological melioidosis are limited. METHODS AND FINDINGS: We established a mouse model of melioidosis with meningitis characterized by neutrophil infiltration into the meninges h...

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Detalles Bibliográficos
Autores principales: Liu, Pei-Ju, Chen, Yao-Shen, Lin, Hsi-Hsu, Ni, Wei-Feng, Hsieh, Tsung-Han, Chen, Hsu-Tzu, Chen, Ya-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738478/
https://www.ncbi.nlm.nih.gov/pubmed/23951382
http://dx.doi.org/10.1371/journal.pntd.0002363