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Ultrasensitivity in Phosphorylation-Dephosphorylation Cycles with Little Substrate
Cellular decision-making is driven by dynamic behaviours, such as the preparations for sunrise enabled by circadian rhythms and the choice of cell fates enabled by positive feedback. Such behaviours are often built upon ultrasensitive responses where a linear change in input generates a sigmoidal ch...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738489/ https://www.ncbi.nlm.nih.gov/pubmed/23950701 http://dx.doi.org/10.1371/journal.pcbi.1003175 |