A Distinct Role of Riplet-Mediated K63-Linked Polyubiquitination of the RIG-I Repressor Domain in Human Antiviral Innate Immune Responses

The innate immune system is essential for controlling viral infections, but several viruses have evolved strategies to escape innate immunity. RIG-I is a cytoplasmic viral RNA sensor that triggers the signal to induce type I interferon production in response to viral infection. RIG-I activation is r...

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Detalles Bibliográficos
Autores principales: Oshiumi, Hiroyuki, Miyashita, Moeko, Matsumoto, Misako, Seya, Tsukasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738492/
https://www.ncbi.nlm.nih.gov/pubmed/23950712
http://dx.doi.org/10.1371/journal.ppat.1003533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738492/
https://www.ncbi.nlm.nih.gov/pubmed/23950712
http://dx.doi.org/10.1371/journal.ppat.1003533

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