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A Systematic Analysis of Host Factors Reveals a Med23-Interferon-λ Regulatory Axis against Herpes Simplex Virus Type 1 Replication

Herpes simplex virus type 1 (HSV-1) is a neurotropic virus causing vesicular oral or genital skin lesions, meningitis and other diseases particularly harmful in immunocompromised individuals. To comprehensively investigate the complex interaction between HSV-1 and its host we combined two genome-sca...

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Detalles Bibliográficos
Autores principales: Griffiths, Samantha J., Koegl, Manfred, Boutell, Chris, Zenner, Helen L., Crump, Colin M., Pica, Francesca, Gonzalez, Orland, Friedel, Caroline C., Barry, Gerald, Martin, Kim, Craigon, Marie H., Chen, Rui, Kaza, Lakshmi N., Fossum, Even, Fazakerley, John K., Efstathiou, Stacey, Volpi, Antonio, Zimmer, Ralf, Ghazal, Peter, Haas, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738494/
https://www.ncbi.nlm.nih.gov/pubmed/23950709
http://dx.doi.org/10.1371/journal.ppat.1003514