Cytomegalovirus Downregulates IRE1 to Repress the Unfolded Protein Response

During viral infection, a massive demand for viral glycoproteins can overwhelm the capacity of the protein folding and quality control machinery, leading to an accumulation of unfolded proteins in the endoplasmic reticulum (ER). To restore ER homeostasis, cells initiate the unfolded protein response...

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Detalles Bibliográficos
Autores principales: Stahl, Sebastian, Burkhart, Julia M., Hinte, Florian, Tirosh, Boaz, Mohr, Hermine, Zahedi, René P., Sickmann, Albert, Ruzsics, Zsolt, Budt, Matthias, Brune, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738497/
https://www.ncbi.nlm.nih.gov/pubmed/23950715
http://dx.doi.org/10.1371/journal.ppat.1003544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738497/
https://www.ncbi.nlm.nih.gov/pubmed/23950715
http://dx.doi.org/10.1371/journal.ppat.1003544

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