Cargando…
Cytomegalovirus Downregulates IRE1 to Repress the Unfolded Protein Response
During viral infection, a massive demand for viral glycoproteins can overwhelm the capacity of the protein folding and quality control machinery, leading to an accumulation of unfolded proteins in the endoplasmic reticulum (ER). To restore ER homeostasis, cells initiate the unfolded protein response...
Autores principales: | Stahl, Sebastian, Burkhart, Julia M., Hinte, Florian, Tirosh, Boaz, Mohr, Hermine, Zahedi, René P., Sickmann, Albert, Ruzsics, Zsolt, Budt, Matthias, Brune, Wolfram |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738497/ https://www.ncbi.nlm.nih.gov/pubmed/23950715 http://dx.doi.org/10.1371/journal.ppat.1003544 |
Ejemplares similares
-
Repression of viral gene expression and replication by the unfolded protein response effector XBP1u
por: Hinte, Florian, et al.
Publicado: (2020) -
Lack of XBP-1 Impedes Murine Cytomegalovirus Gene Expression
por: Drori, Adi, et al.
Publicado: (2014) -
Cytomegalovirus Replicon-Based Regulation of Gene Expression In Vitro and In Vivo
por: Mohr, Hermine, et al.
Publicado: (2012) -
Cytomegaloviruses and Macrophages—Friends and Foes From Early on?
por: Baasch, Sebastian, et al.
Publicado: (2020) -
Activation of E2F-dependent transcription by the mouse cytomegalovirus M117 protein affects the viral host range
por: Ostermann, Eléonore, et al.
Publicado: (2018)