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In Vivo Monitoring of Angiogenesis Inhibition via Down-Regulation of Mir-21 in a VEGFR2-Luc Murine Breast Cancer Model Using Bioluminescent Imaging

MicroRNA-21 (miR-21) is overexpressed in a wide range of cancers and involved in tumor proliferation and metastasis. However, the potential function of miR-21 in regulating tumor angiogenesis has been little disclosed. In this study, we treated the cultured 4T1 murine breast cancer cells and human u...

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Detalles Bibliográficos
Autores principales: Zhao, Dongliang, Tu, Yingfeng, Wan, Lin, Bu, Lihong, Huang, Tao, Sun, Xilin, Wang, Kai, Shen, Baozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738509/
https://www.ncbi.nlm.nih.gov/pubmed/23951172
http://dx.doi.org/10.1371/journal.pone.0071472