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Mapping C-Terminal Transactivation Domains of the Nuclear HER Family Receptor Tyrosine Kinase HER3

Nuclear localized HER family receptor tyrosine kinases (RTKs) have been observed in primary tumor specimens and cancer cell lines for nearly two decades. Inside the nucleus, HER family members (EGFR, HER2, and HER3) have been shown to function as co-transcriptional activators for various cancer-prom...

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Detalles Bibliográficos
Autores principales: Brand, Toni M., Iida, Mari, Luthar, Neha, Wleklinski, Matthew J., Starr, Megan M., Wheeler, Deric L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738522/
https://www.ncbi.nlm.nih.gov/pubmed/23951180
http://dx.doi.org/10.1371/journal.pone.0071518