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Structural Dynamics of Human Telomeric G-Quadruplex Loops Studied by Molecular Dynamics Simulations
Loops which are linkers connecting G-strands and supporting the G-tetrad core in G-quadruplex are important for biological roles of G-quadruplexes. TTA loop is a common sequence which mainly resides in human telomeric DNA (hTel) G-quadruplex. A series of molecular dynamics (MD) simulations were carr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738534/ https://www.ncbi.nlm.nih.gov/pubmed/23951152 http://dx.doi.org/10.1371/journal.pone.0071380 |