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Specific Inhibition of Tumor Cells by Oncogenic EGFR Specific Silencing by RNA interference

Anticancer agents that have minimal effects on normal cells and tissues are ideal cancer drugs. Here, we show specific inhibition of human cancer cells carrying oncogenic mutations in the epidermal growth factor receptor (EGFR) gene by means of oncogenic allele-specific RNA interference (RNAi), both...

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Detalles Bibliográficos
Autores principales: Takahashi, Masaki, Chiyo, Tomoko, Okada, Takashi, Hohjoh, Hirohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738543/
https://www.ncbi.nlm.nih.gov/pubmed/23951344
http://dx.doi.org/10.1371/journal.pone.0073214