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Specific Inhibition of Tumor Cells by Oncogenic EGFR Specific Silencing by RNA interference
Anticancer agents that have minimal effects on normal cells and tissues are ideal cancer drugs. Here, we show specific inhibition of human cancer cells carrying oncogenic mutations in the epidermal growth factor receptor (EGFR) gene by means of oncogenic allele-specific RNA interference (RNAi), both...
Autores principales: | Takahashi, Masaki, Chiyo, Tomoko, Okada, Takashi, Hohjoh, Hirohiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738543/ https://www.ncbi.nlm.nih.gov/pubmed/23951344 http://dx.doi.org/10.1371/journal.pone.0073214 |
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