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Prognostic Significance of ESR1 Amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 Polymorphisms in Breast Cancer Patients

INTRODUCTION: Amplification of the ESR1 gene, coding for estrogen receptor alpha, was shown to predict responsiveness to tamoxifen, however its prognostic impact in breast cancer patients has not been thoroughly investigated. Other factors that could contribute to responsiveness to tamoxifen treatme...

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Detalles Bibliográficos
Autores principales: Markiewicz, Aleksandra, Wełnicka-Jaśkiewicz, Marzena, Skokowski, Jarosław, Jaśkiewicz, Janusz, Szade, Jolanta, Jassem, Jacek, Żaczek, Anna J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738574/
https://www.ncbi.nlm.nih.gov/pubmed/23951298
http://dx.doi.org/10.1371/journal.pone.0072219