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Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene
RNA interference (RNAi) is a powerful and widely used approach to investigate gene function, but a major limitation of the approach is the high incidence of non-specific phenotypes that arise due to off-target effects. We previously showed that RNAi-mediated knock-down of pico, which encodes the onl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738578/ https://www.ncbi.nlm.nih.gov/pubmed/23950943 http://dx.doi.org/10.1371/journal.pone.0070489 |