An In Silico Analysis of the Binding Modes and Binding Affinities of Small Molecule Modulators of PDZ-Peptide Interactions

Inhibitors of PDZ-peptide interactions have important implications in a variety of biological processes including treatment of cancer and Parkinson’s disease. Even though experimental studies have reported characterization of peptidomimetic inhibitors of PDZ-peptide interactions, the binding modes f...

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Detalles Bibliográficos
Autores principales: Tiwari, Garima, Mohanty, Debasisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738590/
https://www.ncbi.nlm.nih.gov/pubmed/23951139
http://dx.doi.org/10.1371/journal.pone.0071340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738590/
https://www.ncbi.nlm.nih.gov/pubmed/23951139
http://dx.doi.org/10.1371/journal.pone.0071340

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