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NCI-H295R, a Human Adrenal Cortex-Derived Cell Line, Expresses Purinergic Receptors Linked to Ca(2+)-Mobilization/Influx and Cortisol Secretion

Purinergic receptor expression and involvement in steroidogenesis were examined in NCI-H295R (H295R), a human adrenal cortex cell line which expresses all the key enzymes necessary for steroidogenesis. mRNA/protein for multiple P1 (A(2A) and A(2B)), P2X (P2X(5) and P2X(7)), and P2Y (P2Y(1), P2Y(2),...

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Detalles Bibliográficos
Autores principales: Nishi, Haruhisa, Arai, Hirokazu, Momiyama, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738630/
https://www.ncbi.nlm.nih.gov/pubmed/23951072
http://dx.doi.org/10.1371/journal.pone.0071022