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Epithelial V-Like Antigen Mediates Efficacy of Anti-Alpha(4) Integrin Treatment in a Mouse Model of Multiple Sclerosis

Natalizumab inhibits the transmigration of activated T lymphocytes into the brain and is highly efficacious in multiple sclerosis (MS). However, from a pharmacogenomic perspective, its efficacy and safety in specific patients remain unclear. Here our goal was to analyze the effects of epithelial V-l...

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Detalles Bibliográficos
Autores principales: Wright, Erik, Rahgozar, Kusha, Hallworth, Nicholas, Lanker, Stefan, Carrithers, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738635/
https://www.ncbi.nlm.nih.gov/pubmed/23951051
http://dx.doi.org/10.1371/journal.pone.0070954