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Epithelial V-Like Antigen Mediates Efficacy of Anti-Alpha(4) Integrin Treatment in a Mouse Model of Multiple Sclerosis
Natalizumab inhibits the transmigration of activated T lymphocytes into the brain and is highly efficacious in multiple sclerosis (MS). However, from a pharmacogenomic perspective, its efficacy and safety in specific patients remain unclear. Here our goal was to analyze the effects of epithelial V-l...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738635/ https://www.ncbi.nlm.nih.gov/pubmed/23951051 http://dx.doi.org/10.1371/journal.pone.0070954 |