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Binding of Dopamine to Alpha-Synuclein is Mediated by Specific Conformational States
Parkinson’s disease is the second most common neurodegenerative disorder, in which both alpha-synuclein (α-syn) and dopamine (DA) have a critical role. α-Syn is known to be natively unstructured in equilibrium with subpopulations of more compact structures. It is these compact structures that are th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738842/ https://www.ncbi.nlm.nih.gov/pubmed/23817832 http://dx.doi.org/10.1007/s13361-013-0676-z |