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A Cell-Based Model of Extracellular-Matrix-Guided Endothelial Cell Migration During Angiogenesis

Angiogenesis, the formation of new blood vessels sprouting from existing ones, occurs in several situations like wound healing, tissue remodeling, and near growing tumors. Under hypoxic conditions, tumor cells secrete growth factors, including VEGF. VEGF activates endothelial cells (ECs) in nearby v...

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Detalles Bibliográficos
Autores principales: Daub, Josephine T., Merks, Roeland M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738846/
https://www.ncbi.nlm.nih.gov/pubmed/23494144
http://dx.doi.org/10.1007/s11538-013-9826-5