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A Cell-Based Model of Extracellular-Matrix-Guided Endothelial Cell Migration During Angiogenesis
Angiogenesis, the formation of new blood vessels sprouting from existing ones, occurs in several situations like wound healing, tissue remodeling, and near growing tumors. Under hypoxic conditions, tumor cells secrete growth factors, including VEGF. VEGF activates endothelial cells (ECs) in nearby v...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738846/ https://www.ncbi.nlm.nih.gov/pubmed/23494144 http://dx.doi.org/10.1007/s11538-013-9826-5 |