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Sample size re-assessment leading to a raised sample size does not inflate type I error rate under mild conditions
BACKGROUND: One major concern with adaptive designs, such as the sample size adjustable designs, has been the fear of inflating the type I error rate. In (Stat Med 23:1023-1038, 2004) it is however proven that when observations follow a normal distribution and the interim result show promise, meanin...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738874/ https://www.ncbi.nlm.nih.gov/pubmed/23870495 http://dx.doi.org/10.1186/1471-2288-13-94 |