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Association of telomere shortening in myocardium with heart weight gain and cause of death

We attempted to clarify myocardial telomere dynamics using samples from 530 autopsied patients using Southern blot analysis. Overall regression analysis demonstrated yearly telomere reduction rate of 20 base pairs in the myocardium. There was a significant correlation between myocardial telomere and...

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Detalles Bibliográficos
Autores principales: Terai, Masanori, Izumiyama-Shimomura, Naotaka, Aida, Junko, Ishikawa, Naoshi, Sawabe, Motoji, Arai, Tomio, Fujiwara, Mutsunori, Ishii, Akio, Nakamura, Ken-ichi, Takubo, Kaiyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738945/
https://www.ncbi.nlm.nih.gov/pubmed/23929129
http://dx.doi.org/10.1038/srep02401