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Association of telomere shortening in myocardium with heart weight gain and cause of death
We attempted to clarify myocardial telomere dynamics using samples from 530 autopsied patients using Southern blot analysis. Overall regression analysis demonstrated yearly telomere reduction rate of 20 base pairs in the myocardium. There was a significant correlation between myocardial telomere and...
Autores principales: | Terai, Masanori, Izumiyama-Shimomura, Naotaka, Aida, Junko, Ishikawa, Naoshi, Sawabe, Motoji, Arai, Tomio, Fujiwara, Mutsunori, Ishii, Akio, Nakamura, Ken-ichi, Takubo, Kaiyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738945/ https://www.ncbi.nlm.nih.gov/pubmed/23929129 http://dx.doi.org/10.1038/srep02401 |
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