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Arrhythmogenesis Toxicity of Aconitine Is Related to Intracellular Ca(2+) Signals

Aconitine is a well-known arrhythmogenic toxin and induces triggered activities through cardiac voltage-gated Na(+) channels. However, the effects of aconitine on intracellular Ca(2+) signals were previously unknown. We investigated the effects of aconitine on intracellular Ca(2+) signals in rat ven...

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Detalles Bibliográficos
Autores principales: Zhou, Yu-hong, Piao, Xian-mei, Liu, Xue, Liang, Hai-hai, Wang, Lei-min, Xiong, Xue-hui, Wang, Lu, Lu, Yan-jie, Shan, Hong-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739024/
https://www.ncbi.nlm.nih.gov/pubmed/23935402
http://dx.doi.org/10.7150/ijms.6541