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Amyloid-Beta Induced CA1 Pyramidal Cell Loss in Young Adult Rats Is Alleviated by Systemic Treatment with FGL, a Neural Cell Adhesion Molecule-Derived Mimetic Peptide

Increased levels of neurotoxic amyloid-beta in the brain are a prominent feature of Alzheimer’s disease. FG-Loop (FGL), a neural cell adhesion molecule-derived peptide that corresponds to its second fibronectin type III module, has been shown to provide neuroprotection against a range of cellular in...

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Detalles Bibliográficos
Autores principales: Corbett, Nicola J., Gabbott, Paul L., Klementiev, Boris, Davies, Heather A., Colyer, Frances M., Novikova, Tatiana, Stewart, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739720/
https://www.ncbi.nlm.nih.gov/pubmed/23951173
http://dx.doi.org/10.1371/journal.pone.0071479