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Amyloid-Beta Induced CA1 Pyramidal Cell Loss in Young Adult Rats Is Alleviated by Systemic Treatment with FGL, a Neural Cell Adhesion Molecule-Derived Mimetic Peptide
Increased levels of neurotoxic amyloid-beta in the brain are a prominent feature of Alzheimer’s disease. FG-Loop (FGL), a neural cell adhesion molecule-derived peptide that corresponds to its second fibronectin type III module, has been shown to provide neuroprotection against a range of cellular in...
Autores principales: | Corbett, Nicola J., Gabbott, Paul L., Klementiev, Boris, Davies, Heather A., Colyer, Frances M., Novikova, Tatiana, Stewart, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739720/ https://www.ncbi.nlm.nih.gov/pubmed/23951173 http://dx.doi.org/10.1371/journal.pone.0071479 |
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