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Pharmacological Inhibition of polysialyltransferase ST8SiaII Modulates Tumour Cell Migration

Polysialic acid (polySia), an α-2,8-glycosidically linked polymer of sialic acid, is a developmentally regulated post-translational modification predominantly found on NCAM (neuronal cell adhesion molecule). Whilst high levels are expressed during development, peripheral adult organs do not express...

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Detalles Bibliográficos
Autores principales: Al-Saraireh, Yousef M. J., Sutherland, Mark, Springett, Bradley R., Freiberger, Friedrich, Ribeiro Morais, Goreti, Loadman, Paul M., Errington, Rachel J., Smith, Paul J., Fukuda, Minoru, Gerardy-Schahn, Rita, Patterson, Laurence H., Shnyder, Steven D., Falconer, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739731/
https://www.ncbi.nlm.nih.gov/pubmed/23951351
http://dx.doi.org/10.1371/journal.pone.0073366