A Type-II Positive Allosteric Modulator of α7 nAChRs Reduces Brain Injury and Improves Neurological Function after Focal Cerebral Ischemia in Rats

In the absence of clinically-efficacious therapies for ischemic stroke there is a critical need for development of new therapeutic concepts and approaches for prevention of brain injury secondary to cerebral ischemia. This study tests the hypothesis that administration of PNU-120596, a type-II posit...

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Detalles Bibliográficos
Autores principales: Sun, Fen, Jin, Kunlin, Uteshev, Victor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739732/
https://www.ncbi.nlm.nih.gov/pubmed/23951360
http://dx.doi.org/10.1371/journal.pone.0073581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739732/
https://www.ncbi.nlm.nih.gov/pubmed/23951360
http://dx.doi.org/10.1371/journal.pone.0073581

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