Trichostatin A Modulates Thiazolidinedione-Mediated Suppression of Tumor Necrosis Factor α-Induced Lipolysis in 3T3-L1 Adipocytes

In obesity, high levels of tumor necrosis factor α (TNFα) stimulate lipolysis in adipocytes, leading to hyperlipidemia and insulin resistance. Thiazolidinediones (TZDs), the insulin-sensitizing drugs, antagonize TNFα-induced lipolysis in adipocytes, thereby increasing insulin sensitivity in diabetes...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Juu-Chin, Chang, Yu-Tzu, Wang, Chih-Tien, Lin, Yu-Chun, Lin, Chun-Ken, Wu, Zhong-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739734/
https://www.ncbi.nlm.nih.gov/pubmed/23951179
http://dx.doi.org/10.1371/journal.pone.0071517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739734/
https://www.ncbi.nlm.nih.gov/pubmed/23951179
http://dx.doi.org/10.1371/journal.pone.0071517

Ejemplares similares