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Immunohistochemical, Ultrastructural and Functional Analysis of Axonal Regeneration through Peripheral Nerve Grafts Containing Schwann Cells Expressing BDNF, CNTF or NT3

We used morphological, immunohistochemical and functional assessments to determine the impact of genetically-modified peripheral nerve (PN) grafts on axonal regeneration after injury. Grafts were assembled from acellular nerve sheaths repopulated ex vivo with Schwann cells (SCs) modified to express...

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Detalles Bibliográficos
Autores principales: Godinho, Maria João, Teh, Lip, Pollett, Margaret A., Goodman, Douglas, Hodgetts, Stuart I., Sweetman, Iain, Walters, Mark, Verhaagen, Joost, Plant, Giles W., Harvey, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739754/
https://www.ncbi.nlm.nih.gov/pubmed/23950907
http://dx.doi.org/10.1371/journal.pone.0069987