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Chronic Alcohol-Induced microRNA-155 Contributes to Neuroinflammation in a TLR4-Dependent Manner in Mice

INTRODUCTION: Alcohol-induced neuroinflammation is mediated by pro-inflammatory cytokines and chemokines including tumor necrosis factor-α (TNFα), monocyte chemotactic protein-1 (MCP1) and interleukin-1-beta (IL-1β). Toll-like receptor-4 (TLR4) pathway induced nuclear factor-κB (NF-κB) activation is...

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Detalles Bibliográficos
Autores principales: Lippai, Dora, Bala, Shashi, Csak, Timea, Kurt-Jones, Evelyn A., Szabo, Gyongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739772/
https://www.ncbi.nlm.nih.gov/pubmed/23951048
http://dx.doi.org/10.1371/journal.pone.0070945