MicroRNA-185 and 342 Inhibit Tumorigenicity and Induce Apoptosis through Blockade of the SREBP Metabolic Pathway in Prostate Cancer Cells

MicroRNA (miRNA or miR) inhibition of oncogenic related pathways has been shown to be a promising therapeutic approach for cancer. Aberrant lipid and cholesterol metabolism is involved in prostate cancer development and progression to end-stage disease. We recently demonstrated that a key transcript...

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Detalles Bibliográficos
Autores principales: Li, Xiangyan, Chen, Yi-Ting, Josson, Sajni, Mukhopadhyay, Nishit K., Kim, Jayoung, Freeman, Michael R., Huang, Wen-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739799/
https://www.ncbi.nlm.nih.gov/pubmed/23951060
http://dx.doi.org/10.1371/journal.pone.0070987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739799/
https://www.ncbi.nlm.nih.gov/pubmed/23951060
http://dx.doi.org/10.1371/journal.pone.0070987

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