Cargando…

Structural Guided Scaffold Phage Display Libraries as a Source of Bio-Therapeutics

We have developed a structurally-guided scaffold phage display strategy for identification of ligand mimetic bio-therapeutics. As a proof of concept we used the ligand of integrin αvβ6, a tumour cell surface receptor and a major new target for imaging and therapy of many types of solid cancer. NMR s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Man, Y. K. Stella, DiCara, Danielle, Chan, Nicole, Vessillier, Sandrine, Mather, Stephen J., Rowe, Michelle L., Howard, Mark J., Marshall, John F., Nissim, Ahuva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739823/ https://www.ncbi.nlm.nih.gov/pubmed/23950939 http://dx.doi.org/10.1371/journal.pone.0070452

Ejemplares similares

Targeted delivery of cytokine therapy to rheumatoid tissue by a synovial targeting peptide
por: Wythe, Sarah E, et al.
Publicado: (2013)

Phage Display Libraries Identify T Cells
Publicado: (2004)

Antibody Phage Display Libraries: Contributions to Oncology
por: Dantas-Barbosa, Carmela, et al.
Publicado: (2012)

Miniproteins as Phage Display-Scaffolds for Clinical Applications
por: Zoller, Frederic, et al.
Publicado: (2011)

Phage Display Libraries for Antibody Therapeutic Discovery and Development
por: Almagro, Juan C., et al.
Publicado: (2019)

Genetically Encoded Cyclic Peptide Phage Display Libraries
por: Simonetti, Leandro, et al.
Publicado: (2020)

Evolution of phage display libraries for therapeutic antibody discovery
por: Zhang, Yang
Publicado: (2023)

Protocol for design, construction, and selection of genome phage (gPhage) display libraries
por: Rodriguez Carnero, Luis Antonio, et al.
Publicado: (2021)

Design of an artificial phage-display library based on a new scaffold improved for average stability of the randomized proteins
por: Gomes, M., et al.
Publicado: (2023)

Phage display peptide libraries: deviations from randomness and correctives
por: Ryvkin, Arie, et al.
Publicado: (2018)

Diversity of Phage-Displayed Libraries of Peptides during Panning and Amplification
por: Derda, Ratmir, et al.
Publicado: (2011)

Phage Display of Combinatorial Peptide Libraries: Application to Antiviral Research
por: Castel, Guillaume, et al.
Publicado: (2011)

Diversity of the Antibody Response to Tetanus Toxoid: Comparison of Hybridoma Library to Phage Display Library
por: Sorouri, Mahsa, et al.
Publicado: (2014)

Propagation Capacity of Phage Display Peptide Libraries Is Affected by the Length and Conformation of Displayed Peptide
por: Kamstrup Sell, Danna, et al.
Publicado: (2023)

Construction of a T7 phage display nanobody library for bio-panning and identification of chicken dendritic cell-specific binding nanobodies
por: Xu, Hai, et al.
Publicado: (2022)

Trinucleotide cassettes increase diversity of T7 phage-displayed peptide library
por: Krumpe, Lauren RH, et al.
Publicado: (2007)

The Use of Phage-Displayed Peptide Libraries to Develop Tumor-Targeting Drugs
por: Krumpe, Lauren R.H., et al.
Publicado: (2006)

Wide Screening of Phage-Displayed Libraries Identifies Immune Targets in Planta
por: Rioja, Cristina, et al.
Publicado: (2013)

Design and Screening of M13 Phage Display cDNA Libraries
por: Georgieva, Yuliya, et al.
Publicado: (2011)

Construction and evaluation of an antibody phage display library targeting heparan sulfate
por: Damen, Lars A.A., et al.
Publicado: (2020)

Evolutionary Qβ Phage Displayed Nanotag Library and Peptides for Biosensing
por: Ntemafack, Augustin, et al.
Publicado: (2023)

Polypharmacy through Phage Display: Selection of Glucagon and GLP-1 Receptor Co-agonists from a Phage-Displayed Peptide Library
por: Demartis, Anna, et al.
Publicado: (2018)

A Novel Helper Phage Enabling Construction of Genome-Scale ORF-Enriched Phage Display Libraries
por: Gupta, Amita, et al.
Publicado: (2013)

Phage Peptide Libraries As a Source of Targeted Ligands
por: Nemudraya, A. A., et al.
Publicado: (2016)

Screening E3 Substrates Using a Live Phage Display Library
por: Guo, Zhengguang, et al.
Publicado: (2013)

Discovery of Surfactant-Like Peptides from a Phage-Displayed Peptide Library
por: Sawada, Toshiki, et al.
Publicado: (2020)

Identification of COVID-19 B-cell epitopes with phage-displayed peptide library
por: Guo, Jing-You, et al.
Publicado: (2021)

Structure-based design and construction of a synthetic phage display nanobody library
por: Moreno, Ernesto, et al.
Publicado: (2022)

Construction and use of Plasmodium falciparum phage display libraries to identify host parasite interactions
por: Lauterbach, Sonja B, et al.
Publicado: (2003)

Epitope mapping using combinatorial phage-display libraries: a graph-based algorithm
por: Mayrose, Itay, et al.
Publicado: (2007)

Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro
por: Tonelli, R. R., et al.
Publicado: (2013)

Selection of peptides binding to metallic borides by screening M13 phage display libraries
por: Ploss, Martin, et al.
Publicado: (2014)

Generation and analysis of the improved human HAL9/10 antibody phage display libraries
por: Kügler, Jonas, et al.
Publicado: (2015)

Detection of Cystic Fibrosis Serological Biomarkers Using a T7 Phage Display Library
por: Talwar, Harvinder, et al.
Publicado: (2017)

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries
por: Shave, Steven, et al.
Publicado: (2018)

Novel T7 Phage Display Library Detects Classifiers for Active Mycobacterium Tuberculosis Infection
por: Talwar, Harvinder, et al.
Publicado: (2018)

Cognizance of Molecular Methods for the Generation of Mutagenic Phage Display Antibody Libraries for Affinity Maturation
por: Lim, Chia Chiu, et al.
Publicado: (2019)

Construction of a Nanobodies Phage Display Library From an Escherichia coli Immunized Dromedary
por: Salhi, Imed, et al.
Publicado: (2020)

Monoclonal Antibodies and Antibody Like Fragments Derived from Immunised Phage Display Libraries
por: Ubah, Obinna, et al.
Publicado: (2018)

Mapping Protein–Protein Interactions with Phage-Displayed Combinatorial Peptide Libraries and Alanine Scanning
por: Kokoszka, Malgorzata E., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_i9g8qsj246skb6abtjfgqedocc