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Cellular Prion Protein (PrP(C)) of the Neuron Cell Transformed to a PK-Resistant Protein Under Oxidative Stress, Comprising Main Mitochondrial Damage in Prion Diseases

Prion diseases characterize a category of fatal neurodegenerative diseases. Although reports have increasingly shown that oxidative stress plays an important role in the progression of prion diseases, little is known about whether oxidative stress is a cause or a consequence of a prion disease. The...

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Detalles Bibliográficos
Autores principales: Yuan, Fangzhong, Yang, Lifeng, Zhang, Zhuming, Wu, Wenyu, Zhou, Xiangmei, Yin, Xiaomin, Zhao, Deming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739867/
https://www.ncbi.nlm.nih.gov/pubmed/23715697
http://dx.doi.org/10.1007/s12031-013-0008-6