HIV proteinase inhibitors target the Ddi1-like protein of Leishmania parasites

HIV proteinase inhibitors reduce the levels of Leishmania parasites in vivo and in vitro, but their biochemical target is unknown. We have identified an ortholog of the yeast Ddi1 protein as the only member of the aspartic proteinase family in Leishmania parasites, and in this study we investigate t...

Descripción completa

Detalles Bibliográficos
Autores principales: White, Rhian E., Powell, David J., Berry, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2011
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739880/
https://www.ncbi.nlm.nih.gov/pubmed/21266539
http://dx.doi.org/10.1096/fj.10-178947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739880/
https://www.ncbi.nlm.nih.gov/pubmed/21266539
http://dx.doi.org/10.1096/fj.10-178947

Ejemplares similares