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Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture

The inner ear contains sensory epithelia that detect head movements, gravity and sound. It is unclear how to derive these sensory epithelia from pluripotent stem cells, a process which will be critical for modeling inner ear disorders or developing cell-based therapies for profound hearing loss and...

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Detalles Bibliográficos
Autores principales: Koehler, Karl R., Mikosz, Andrew M., Molosh, Andrei I., Patel, Dharmeshkumar, Hashino, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739998/
https://www.ncbi.nlm.nih.gov/pubmed/23842490
http://dx.doi.org/10.1038/nature12298